Alopecia Areata is an autoimmune disorder characterized by patches of non-scarring alopecia affecting the scalp and body hair. There is no preventative therapy or cure at this moment. Hair transplantation – which takes plugs of natural hair from hair-rich occipital areas and transplants them to the hair-poor areas- may no longer be a viable option for treatment, as there might not be sufficient donor hair follicles (available from the scalp or other areas) that can be transplanted without causing collateral damage elsewhere.
Female pattern hair loss (FPHL) is the most common type of baldness in women, showing a prevalence of approximately 6% in women aged under 50 years and 38% in women aged 70 years and over. Currently, there are few therapeutic options for women with FPHL: anti-androgen drugs and topical Estrogen are used, but they do not always achieve successful results and are not safe in reproductive women. In order to overcome these problems, cell therapy to restore bald scalp areas has become an emerging focus in addressing this medical condition.
Adipose derived cells (ADC) are one of the latest break-troughs in hair regeneration, since these cells and their conditioned media (ADC-CM) have been reported to promote hair growth in vitro and in some clinical reports of treatments for androgenic alopecia or female pattern hair loss (FPHL).
HAIRSKILL is a very simple procedure that requires the collection of a small amount of adipose tissue that can be harvested in a simple outpatient session. After twelve days the ADSC, extracted from your fat, are injected into the microenvironment surrounding the hair bulb. The injected cells release specific growth factors that prolong the duration of the anagen phase and improve the regeneration of the hair.
WHAT TO EXPECT?
With HAIRSKILL it is now possible to treat progressive weakening of the hair bulb and resulting hair loss. HAIRSKILL is an innovative, effective and safe method based on the use of stem cells derived from adipose tissue.
Initial results are visible in 1 month and they gradually increase over time. The adipose derived stems cells therapy makes Hair Transplants easier because it strengthens and prepares the scalp before the transplant, and stimulates engraftement in the bulb.
It is a biological product and the results vary from patient to patient according to age of the patient. The action of the ASDC is effective only if the bulb is not irreversibly compromised. This procedure is typically used for these patients who are not surgical candidates because they are too young or they are in the early phase of hair loss.
ADC-CM contains various regenerative factors secreted by ADC that can limit hair loss by recruiting endogenous cells to hair follicles sites and triggering regeneration. Moreover, ADC-CM increases the poor engraftment of the ADC transplanted alone and the clinical outcomes in hair regeneration.
The possibility of freezing part of the material offers the advantage of repeating the treatment several times over the years without the need to undergo fat tissue collection again.